The Body Scrubs Notch signalling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear.Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic chick.The chicken homologue of Numb is expressed throughout the otocyst at early sta
Cirrhosis and hepatocellular carcinoma are the prototypic complications of chronic hepatitis C virus infection in the liver.However, hepatitis C virus also affects a variety of other organs that may lead to significant morbidity and mortality.Extrahepatic manifestations of hepatitis C infection include a multitude of disease processes affecting the
Objective: To determine the frequency of different phenotypes for congenital anomalies of the kidney and urinary tract (CAKUT) in a Brazilian sample, and to evaluate the association between the CAKUT phenotypes and the BMP4 gene.Methods: In this study, 457 Brazilian individuals were analyzed in an attempt to establish the association between the BM
Introduction: Radiocephalic arteriovenous fistulas (AVFs) for dialysis have significantly high maturation failure rate.Many surgical technique-related factors are known to impact the outcomes of AVF surgery; anastomotic suturing technique is Developer and Photoconductor Unit Pack one such factor for which the published data is sparse.Patients and M